Fig. 3
The effect of OX40L-Ig fusion protein on proliferation and differentiation of CD4+ T cells. Control: the OVA-primed CD4+ T cells; OVA: the OVA-primed CD4+ T cells treated with Ig; OVA + OX40L-Ig: the OVA-primed CD4+ T cells treated with OX40L-Ig fusion protein. a The proliferation of CD4+ T cells. b–e The expression of OX40L, IFN-γ, IL-4 and IL-17 and TGF-β. f–i Cells count of Th1, Th2, Th17 and Treg. j The phosphorylation and protein expressions levels of Akt, p38 MAPK and GAPDH using Western blot.*OVA + OX40L-Ig group differ significantly (p < 0.05) with control. #OVA + OX40L-Ig group differ significantly (p < 0.05) with OVA