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Table 1 Demographic characteristics and pulmonary function test parameters of the 40 COPD patients and 16 healthy non-smokers

From: Defective formyl peptide receptor 2/3 and annexin A1 expressions associated with M2a polarization of blood immune cells in patients with chronic obstructive pulmonary disease

  Healthy non-smokers
N = 16
COPD patients at diagnosis
N = 40
p value COPD patients followed up after 1-year treatment
N = 10
Age, years 53.9 ± 12.2 63.4 ± 4.5 0.009 69.5 ± 9.5
BMI, kg/m2 25.38 ± 4.6 25 ± 4.2 0.775 24.6 ± 4.6
Smoking exposure, pack-years 0 64.4 ± 40.1 < 0.001 65.5 ± 50.8
Ex-smokers, n (%)   21 (52.2)   7 (70%)
Diabetes mellitus, n (%) 1 (6.3) 5 (12.8) 0.478  
Stroke, n (%) 0 (0) 2 (5.1) 0.356  
Chronic hepatitis, n (%) 1 (6.3) 5 (12.8) 0.478  
Chronic kidney disease, n (%) 0 (0) 5 (12.8) 0.133  
Congestive heart failure, n (%) 0 (0) 0 (0) 1  
Myocardial infarction, n (%) 0 (0) 0 (0) 1  
MMRC score 0.38 ± 0.5 1.49 ± 0.99 < 0.001 1.2 ± 0.79
HbA1c 5.8 ± 0.5 5.9 ± 0.6 0.663 6.0 ± 0.8
Triglyceride 105.7 ± 60.4 119.7 ± 50.2 0.389 146.3 ± 82.7
Cholesterol 187.9 ± 44.4 185.7 ± 36.6 0.853 184.4 ± 38.5
Pre-BD FEV1 %predicted, % 113.18 ± 16.1 57.72 ± 24.56 < 0.001 56.74 ± 12.96
Pre-BD FEV1/FVC, % 81.56 ± 5.4 54.44 ± 15.38 < 0.001 55.03 ± 10.27
Pre-BD FEF25-75%, %predicted 109.6 ± 27.1 26.2 ± 20.4 < 0.001 21.28 ± 9.63
Post-BD FEV1, %predicted N.A. 61.68 ± 22.68   61.7 ± 13.28
Post-BD FEV1/FVC, % N.A. 57.1 ± 13.1   56.74 ± 11.27
Post-BD FEF25–75%, %predicted N.A. 28.8 ± 17.8   25.37 ± 11.14