Table 2 Sorted genes downregulated by hUTC conditioned medium treatment in human RPE cells isolated from AMD and normal donors
IPA category | Function | Gene symbol | Gene name |
|---|---|---|---|
Cellular movement | Rho GTPases related | ARHGAP9 | Rho GTPase activating protein 9 |
Cell death and survival | Apoptosis induction | CYCS | Cytochrome c, somatic |
| Â | BMP5 | Bone morphogenetic protein 5 | |
| Â | Â | EGR3 | Early growth response 3 |
Cellular function and maintenance | Inflammation induction | TLR4 | Toll like receptor 4 |
| Â | TAC1 | Tachykinin precursor 1 | |
| Â | Â | FABP4 | Fatty acid binding protein 4 |
|  |  | CCRL2 | C–C motif chemokine receptor like 2 |
| Â | Â | PTGDR | Prostaglandin D2 receptor |
| Â | Â | F2RL1 | F2R like trypsin receptor 1 |
| Â | Â | PLA2G7 | Phospholipase A2 group VII |