Table 2 Sorted genes downregulated by hUTC conditioned medium treatment in human RPE cells isolated from AMD and normal donors
| IPA category | Function | Gene symbol | Gene name |
|---|---|---|---|
| Cellular movement | Rho GTPases related | ARHGAP9 | Rho GTPase activating protein 9 |
| Cell death and survival | Apoptosis induction | CYCS | Cytochrome c, somatic |
| BMP5 | Bone morphogenetic protein 5 | ||
| EGR3 | Early growth response 3 | ||
| Cellular function and maintenance | Inflammation induction | TLR4 | Toll like receptor 4 |
| TAC1 | Tachykinin precursor 1 | ||
| FABP4 | Fatty acid binding protein 4 | ||
| CCRL2 | C–C motif chemokine receptor like 2 | ||
| PTGDR | Prostaglandin D2 receptor | ||
| F2RL1 | F2R like trypsin receptor 1 | ||
| PLA2G7 | Phospholipase A2 group VII |