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Table 1 Sorted genes upregulated by hUTC conditioned medium treatment in human RPE cells isolated from AMD and normal donors

From: RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells

IPA category Function Gene symbol Gene name
Cellular movement Receptor tyrosine kinase MERTK MER proto-oncogene, tyrosine kinase
  Rho GTPases related PLD1 Phospholipase D1
   PAK3 p21 (RAC1) activated kinase 3
  Growth factors GDNF Glial cell derived neurotrophic factor
Cell death and survival Anti-apoptosis ADM Adrenomedullin
  EPOR Erythropoietin receptor
   SOCS3 Suppressor of cytokine signaling 3
   NR4A2 Nuclear receptor subfamily 4 group A member 2
   PIM1 Pim-1 proto-oncogene, serine/threonine kinase
   GDF9 Growth differentiation factor 9
   BIRC3 Baculoviral IAP repeat containing 3
   G0S2 G0/G1 switch 2
Cellular function and maintenance Anti-inflammation ESR2 Estrogen receptor 2
  NFKBIA NFKB inhibitor alpha
   ZC3H12A Zinc finger CCCH-type containing 12A
  Anti-oxidative stress SOD2 Superoxide dismutase 2, mitochondrial
   ALB Albumin
Lipid metabolism Enzymes ABCA1 ATP binding cassette subfamily A member 1