Fig. 6

Effect of hUTC conditioned medium on gene expression in human RPE cells. a Gene expression changes after 24-h hUTC CM treatment in human normal (X axis) and AMD (Y axis) RPE cells. The changes in gene expression between the two cell types are significantly correlated (P value = 0). b Enrichment of genes modulated by hUTC CM treatment in molecular and cellular functions (adjusted P value < 0.05). 1811 genes significantly upregulated or downregulated (fold change > 2 and adjusted P value < 0.05) in response to hUTC CM treatment were enriched in 19 molecular and cellular functions