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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: The role of atorvastatin in suppressing tumor growth of uterine fibroids

Fig. 3

Effect of atorvastatin on cell proliferation in human uterine fibroids cells. Immortalized human uterine fibroids cells (a) and primary uterine fibroids cells (b) were treated with increasing concentrations of atorvastatin (0, 1, 5, 10, 20 and 40 μM) for 24, 48 or 72 h, and then followed by CCK-8 assay. Data presented were mean ± SEM from triplicate measurements. *P < 0.05 with one-way ANOVA, compared to controls (treated with DMSO). Immortalized human uterine fibroids cells (c) and primary uterine fibroids cells (d) were treated with increasing concentrations of atorvastatin (0, 1,5, 10, 20 and 40 μM) for 48 h (immortalized cells) or 72 h (primary cells) and then followed by western blot analysis. Tubulin was used as the loading control. The intensity of each protein band was quantified and normalized with corresponding tubulin, and the normalized values were used to generate the graphs. Data presented were mean ± SEM from triplicate measurements. *P < 0.05 with one-way ANOVA

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