PANTHER classification pathways
|
Number of genes
|
Over-/under-represented (±)
|
Fold enrichment
|
P value
|
---|
Reference lista
|
Target listb
|
Expectedc
|
---|
Apoptosis signaling pathway (P00006)
|
119
|
10
|
1.68
|
+
|
5.96
|
0.00154
|
JAK/STAT signaling pathway (P00038)
|
17
|
4
|
0.24
|
+
|
16.69
|
0.00210
|
Integrin signalling pathway (P00034)
|
194
|
11
|
2.73
|
+
|
4.02
|
0.01920
|
Angiogenesis (P00005)
|
174
|
10
|
2.45
|
+
|
4.08
|
0.03500
|
- Pathways resulted significantly over-represented by the identified protein coding genes. P values were tested using Fisher exact test and adjusted using a Bonferroni correction test. MFS Marfan syndrome, HVs healthy volunteers
- a Number of genes in the reference list that map to this PANTHER classification category
- b Number of genes in the target genes list that map to this PANTHER classification category
- c Expected value is the number of genes that could be expected in target genes list for this PANTHER category based on the reference list