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Table 2 Medical therapies used prior to start of LDN and concomitantly with LDN

From: Low dose Naltrexone for induction of remission in inflammatory bowel disease patients

 

UC, 19

CD, 28

Combined, 47

Prior and concomitant therapies

 Therapies prior to LDN, N (%)

  5-ASA

17 (89%)

14 (50%)

31 (66%)

  Steroids

19 (100%)

28 (100%)

47 (100%)

  Immunosuppressives

18 (95%)

27 (96%)

45 (96%)

  Anti-TNF

16 (84%)

25 (89%)

41 (87%)

  Other

5 (26%)

2 (7%)

8 (15%)

 Concomitant therapies at start of LDN, N (%)

  5-ASA

7 (37%)

3 (11%)

10 (21%)

  Steroids

6 (32%)

18 (64%)

24 (51%)

  Immunosuppressives

8 (42%)

9 (32%)

17 (36%)

  Anti-TNF

5 (26%)

3 (11%)

8 (17%)

  Other

1 (5%)

2 (7%)

3 (6%)

  None

4 (21%)

7 (25%)

11 (23%)

  1. Steroids refer to any form of corticosteroids. Immunosuppressives refer to thiopurines or methotrexate. Other refers to tacrolimus, cyclosporine, thioguanine or blinded trial drugs
  2. anti-TNF anti-tumor necrosis factor, CD Crohn’s disease, LDN low dose Naltrexone, UC ulcerative colitis