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Table 1 Core analysis of the kidney in 6-week-old mice

From: Physiological and molecular effects of interleukin-18 administration on the mouse kidney

Diseases or functions annotation

p-value

Molecules

Delayed hypersensitive reaction of renal glomerulus

4.92E−03

Il18

Injury of kidney

3.50E−02

Il18, Ppard

Injury of endothelial cells

4.92E−03

Itgam

Thrombosis of blood

4.92E−03

Itgam

Recruitment of neutrophils

9.83E−03

Itgam

Accumulation of neutrophils

1.96E−02

Itgam

Generation of reactive oxygen species

2.92E−02

Itgam

Concentration of retinol

9.83E−03

Lrat

Hypertrophy of renal glomerulus

1.27E−02

Mapk8, Stab 2

Congestion of vasculature

1.96E−02

Nov

Aggregation of mesenchymal cells

4.92E−03

Pax2

Abnormal morphology of renal calyx

9.83E−03

Pax2

Development of renal calyx

9.83E−03

Pax2

Organogenesis of kidney

9.83E−03

Pax2

Size of renal medulla

9.83E−03

Pax2

Hypoplasia of renal cortex

1.47E−02

Pax2

Development of epithelial cells

1.96E−02

Pax2

Injury of outer medulla

4.92E−03

Ppard

Injury of renal cortex

9.83E−03

Ppard

Fibrosis of renal glomerulus

3.87E−02

Stab 2