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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Distinct alterations of CD68+CD163+ M2-like macrophages and myeloid-derived suppressor cells in newly diagnosed primary immune thrombocytopenia with or without CR after high-dose dexamethasone treatment

Fig. 4

Plasma cytokines correlated with M2-like macrophages and MDSCs. Plasma levels of MIP-1α/CCL3 (a), MCP-1 (b), Eotaxin-1/CCL11 (c) and IL-1β (d) in ITP patients. Correlations were found between MDSCs with plasma levels of IL-1β, MIP-1α/CCL3, and MCP-1; between M2-like macrophages with plasma levels of IL-1β and Eotaxin-1/CCL11 (e). ***p < 0.001, **p < 0.01, *p < 0.05, ITP (n = 23) compared to HC (n = 10) in two-tailed Mann–Whitney U test; ###p < 0.001, ##p < 0.01 after treatment vs. before treatment in corresponding CR group (n = 13) and PR + NR group (n = 10) in two-tailed Mann–Whitney U test

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