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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Distinct alterations of CD68+CD163+ M2-like macrophages and myeloid-derived suppressor cells in newly diagnosed primary immune thrombocytopenia with or without CR after high-dose dexamethasone treatment

Fig. 1

Peripheral MDSCs and M2-like macrophages in newly diagnosed ITP patients (n = 33) before treatment and health control (n = 18). a Representative dot plots of CD11b+CD33+HLA-DR MDSCs in the PBMCs of HC and ITP patients. b Representative dot plots of CD68+CD163+ M2-like macrophages in the PBMCs of HC and ITP patients. c Peripheral MDSCs were significantly elevated in ITP patients, with no respect of their later treatment response to HD-DXM regimen. d Peripheral M2-like macrophages were not found elevated in ITP patients, with no respect of their later treatment response to HD-DXM regimen. ***p < 0.001, compared to HC in two-tailed Student’s non-paired t test. Bars represented SD

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