TY - JOUR AU - Shao, Xia AU - Wu, Boting AU - Cheng, Luya AU - Li, Feng AU - Zhan, Yanxia AU - Liu, Chanjuan AU - Ji, Lili AU - Min, Zhihui AU - Ke, Yang AU - Sun, Lihua AU - Chen, Hao AU - Cheng, Yunfeng PY - 2018 DA - 2018/03/02 TI - Distinct alterations of CD68+CD163+ M2-like macrophages and myeloid-derived suppressor cells in newly diagnosed primary immune thrombocytopenia with or without CR after high-dose dexamethasone treatment JO - Journal of Translational Medicine SP - 48 VL - 16 IS - 1 AB - Although impaired myeloid-derived suppressor cells (MDSCs) recently have been studied in immune thrombocytopenia (ITP), another myeloid-derived cell population signified as M2 macrophages has not been investigated properly in ITP patients. In the present study, we intended to determine the features of circulating M2-like macrophages, to examine its relationship with MDSCs, and to explore their prognostic values in ITP. SN - 1479-5876 UR - https://doi.org/10.1186/s12967-018-1424-8 DO - 10.1186/s12967-018-1424-8 ID - Shao2018 ER -