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Table 1 The IC50 values of Apatinib in treating B- and T-lineage ALL cell lines

From: Apatinib exhibits anti-leukemia activity in preclinical models of acute lymphoblastic leukemia

All cell lines

IC50 ± S.D (μmol/L)

P value

48 h

72 h

Nalm6

55.76 ± 13.19

30.34 ± 2.65

0.031

Reh

51.53 ± 10.74

31.96 ± 3.92

0.041

Jurkat

32.43 ± 5.58

17.62 ± 5.90

0.034

Molt4

39.91 ± 9.88

17.65 ± 2.17

0.019