Fig. 2From: Apatinib exhibits anti-leukemia activity in preclinical models of acute lymphoblastic leukemiaApatinib induces apoptosis of both B and T lineage ALL cells in a dose and time-dependent manner. B-lineage (a, b) and T-lineage ALL cells (c, d) were treated with indicated doses of Apatinib for 48 or 72 h, and the percentage of apoptotic cells was examined by Annexin V/PI double staining. *P < 0.05; **P < 0.01; ***P < 0.001Back to article page