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Table 1 Genotype frequencies of single nucleotide polymorphisms (SNP) in fibromyalgia (FM) and non-fibromyalgia (control) women

From: Identification of candidate genes associated with fibromyalgia susceptibility in southern Spanish women: the al-Ándalus project

SNP (gene) Genotype/allele FM,
n (%)
Control,
n (%)
OR
(95% CI, lower to upper)
p value
rs841 (GCH1) AA/AG 72 (23.2) 37 (33.3) 1.66 (1.03–2.67) 0.04
GG 239 (76.8) 74 (66.7)
A 76 (12.2) 40 (18.0) 1.58 (1.04–2.40) 0.03
G 546 (87.8) 182 (82.0)
rs1799971 (OPRM1) AA/AG 137 (44.2) 64 (57.7) 1.72 (1.11–2.67) 0.02
GG 173 (55.8) 47 (42.3)
A 163 (26.3) 78 (35.1) 1.52 (1.09–2.11) 0.01
G 457 (73.7) 144 (64.9)
rs2097903 (COMT) AA 64 (21.2) 34 (30.9) 1.66 (1.02–2.71) 0.04
AT/TT 238 (78.8) 76 (69.1)
A 274 (45.4) 116 (52.7) 1.34 (0.99–1.83) 0.06
T 330 (54.6) 104 (47.3)
  1. Logistic regression analyses were conducted to calculate de odds ratio (OR) and 95% confidence interval (95% CI)
  2. COMT catechol-O-methyltransferase gene, GCH1 GTP cyclohydrolase 1 gene, OPRM1 opioid receptor μ1 gene, A Adenine, C Cytosine, G Guanine, T Thymine