Table 1 Genotype frequencies of single nucleotide polymorphisms (SNP) in fibromyalgia (FM) and non-fibromyalgia (control) women
SNP (gene) | Genotype/allele | FM, n (%) | Control, n (%) | OR (95% CI, lower to upper) | p value |
|---|---|---|---|---|---|
rs841 (GCH1) | AA/AG | 72 (23.2) | 37 (33.3) | 1.66 (1.03–2.67) | 0.04 |
GG | 239 (76.8) | 74 (66.7) | |||
A | 76 (12.2) | 40 (18.0) | 1.58 (1.04–2.40) | 0.03 | |
G | 546 (87.8) | 182 (82.0) | |||
rs1799971 (OPRM1) | AA/AG | 137 (44.2) | 64 (57.7) | 1.72 (1.11–2.67) | 0.02 |
GG | 173 (55.8) | 47 (42.3) | |||
A | 163 (26.3) | 78 (35.1) | 1.52 (1.09–2.11) | 0.01 | |
G | 457 (73.7) | 144 (64.9) | |||
rs2097903 (COMT) | AA | 64 (21.2) | 34 (30.9) | 1.66 (1.02–2.71) | 0.04 |
AT/TT | 238 (78.8) | 76 (69.1) | |||
A | 274 (45.4) | 116 (52.7) | 1.34 (0.99–1.83) | 0.06 | |
T | 330 (54.6) | 104 (47.3) |