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Table 6 Significant telomere attrition in CFS, CFS-X and ISF in comparison to NF in analysis restricted to female participants only

From: Association of chronic fatigue syndrome with premature telomere attrition

CFS-status (all female, n = 477)

T/S ratio

Mean TRF length (bp) difference with respect to NFa

Equivalent additional years in aging with respect to NF

β

SE

p-value

CFS (n = 58) vs. NF (n = 133)

− 0.226

0.0566

< 0.0001

957

15.2–30.9

CFS-X (n = 64) vs. NF

− 0.163

0.0548

0.003

690

11.0–22.3

ISF (n = 222) vs. NF

− 0.168

0.0395

< 0.0001

711

11.3–23.0

  1. Data not shown for male participants since there was no significant difference in telomere length between illness groups in male participants (n = 162)
  2. aTRF length (bp) refers to terminal restriction fragment length in base pairs