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Table 3 Baseline monocyte Telomere lengths according to demographic and clinical characteristics

From: Telomere attrition in heart failure: a flow-FISH longitudinal analysis of circulating monocytes

 

n = 101

p

Age (years)

R = − 0.17

0.09

Sex

0.44

 Male

10.2 ± 2.9

 

 Female

10.7 ± 4.2

 

Etiology

0.90§

 Ischemic heart disease

10.4 ± 3.5

 

 Dilated cardiomyopathy

10.3 ± 4.4

 

 Hypertensive cardiomyopathy

10.5 ± 3.0

 

 Alcoholic cardiomyopathy

9.5 ± 1.8

 

 Valvular disease

9.1 ± 1.8

 

 Hypertrophic cardiomyopathy

11.3 ± 3.3

 

 Other

10.9 ± 2.5

 

HF duration in months

Rho = − 0.13

0.20

LVEF

R = 0.14

0.18

NYHA functional class

0.85§

 I

10.4 ± 3.5

 

 II

10.4 ± 3.6

 

 III

10.0 ± 3.3

 

Hypertension

0.66

 Yes

10.2 ± 3.5

 

 No

10.5 ± 2.3

 

Diabetes mellitus

0.24

 Yes

10.7 ± 3.4

 

 No

9.9 ± 3.1

 

Renal failurea

0.31

 Yes

10.0 ± 2.8

 

 No

10.6 ± 3.6

 

Anemiab

0.23

 Yes

10.8 ± 3.1

 

 No

10.0 ± 3.3

 

Atrial fibrillation/flutter

0.01

 Yes

9.3 ± 2.6

 

 No

11 ± 3.5

 

Obesity

0.23

 Yes

10.9 ± 3.6

 

 No

10.1 ± 3.1

 

Smoker

0.48

 No

10.4 ± 3.3

 

 Past

10.3 ± 3.3

 

 Current

8.6 ± 2.4

 
  1. Data expressed as mean ± standard deviation, median (25th–75th percentiles), or absolute number (percentage). R and Rho according to Pearson and Spearman correlation, respectively
  2. LVEF left ventricular ejection fraction, NYHA New York Heart Association
  3. §Scheffe post hoc analyses did not reveal any statistical difference between individual items
  4. aeGFR < 60 ml/min/1.73 m2
  5. bHb of < 12 g/dl in women and < 13 g/dl in men