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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer

Fig. 6

Germline transmission of GHR-modified alleles. a Picture of partial GHRKO F1 pigs; the leftmost pig is wild-type. b Picture of GHRKO F2 pigs. c PCR products harboring the targeted GHR region amplified from GHRKO F1 pigs. d Detection of the GHR genotype by the T7ENI cleavage assay in GHRKO F1 pigs (M, DNA maker DL2000; WT, PCR product amplified from wild-type pig digested by T7ENI). e Sequences of modified GHR detected in GHRKO F1 and F2 pigs

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Journal of Translational Medicine

ISSN: 1479-5876

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