Fig. 5

Receiver operating characteristic (ROC) curves. a ROC curves derived from logistic regression models, using day-14 concentrations of IL-10 alone (pink line, AUC: 0.77, 95% CI [0.767, 0.777]); TIMP-1 alone (cyan line, AUC: 0.79, 95% CI [0.784, 0.795]); fibronectin alone (green line, AUC: 0.80, 95% CI [0.794, 0.806]); TIMP-1 and IL-10 (red line, AUC: 0.81, 95% CI [0.806, 0.816]); fibronectin and TIMP-1 (brown line, AUC: 0.81, 95% CI [0.807, 0.818]), fibronectin and IL-10 (blue line, AUC: 0.82, 95% CI [0.811, 0.821]); and fibronectin, TIMP-1, and IL-10 (black line, AUC: 0.82, 95% CI [0.818, 0.829]). b ROC curve for tenfold cross validation performed by using day-14 concentrations of fibronectin, TIMP-1, and IL-10 as predictors (AUC: 0.80, 95% CI [0.792, 0.807]). c ROC curves derived from logistic regression models, using day-21 concentrations of IL-10 alone (pink line, AUC: 0.83, 95% CI [0.834, 0.842]); TIMP-1 alone (cyan line, AUC: 0.84, 95% CI [0.840, 0.848]); fibronectin alone (green line, AUC: 0.86, 95% CI [0.859, 0.866]); TIMP-1 and IL-10 (red line, AUC: 0.87, 95% CI [0.866, 0.873]); fibronectin and TIMP-1 (brown line, AUC: 0.87, 95% CI [0.875, 0.882]); fibronectin and IL-10 (blue line, AUC: 0.88, 95% CI [0.876, 0.883]); and fibronectin, TIMP-1, and IL-10 (black line, AUC: 0.89, 95% CI [0.884, 0.891]). d ROC for tenfold cross validation performed by using day-21 concentrations of fibronectin, TIMP-1, and IL-10 as predictors (AUC: 0.86, 95% CI [0.855, 0.870])