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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients

Fig. 2

Disease effects (COPD-DE) network modules. a The four network modules associated to COPD disease effects and their composing genes. Genes are colored according to their differential regulation, namely: up regulation—red nodes; and down regulation—blue nodes. Significantly differentially expressed genes are indicated by * (FDR ≤ 0.05) (for detailed information see Additional file 2: Table S6). b The significant correlations of independent measurements with any of the network modules’ first three principal components. Blue squares depict exercise related independent variables [19]; red squares show cytokines measured in blood [20]; yellow squares correspond to amino acids measured in serum [19]; and, green squares represents redox biomarkers [20]

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