Table 8 Typical examples of nVGDS for stem cell based tissue repair and regeneration
From: Non-viral gene delivery systems for tissue repair and regeneration
Chemical vector | Scaffold/matrices | Cell | DNA/RNA | References |
|---|---|---|---|---|
Polyethylenimine (PEI) | None | hMSCs | pDNA-green fluorescent protein (GFP) | [166] |
Nanohydroxyapatite (nHA) particles | Collagen-nanohydroxyapatite | hMSCs | Reporter miRNAs (nanomiRs) | [168] |
Spermine-introduced pullulan (spermine–pullulan) | Three-dimensional scaffolds of gelatin and beta-tricalcium phosphate (beta-TCP) | Rat MSCs | pDNA-Luciferase | [167] |
Caged nanoparticle encapsulation (CnE) technique | Hyaluronic acid hydrogels | mMSCs | Reporter gene | [169] |