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Table 1 Baseline characteristics of 123 patients with hypopharyngeal squamous cell carcinoma

From: The prognostic value of preoperative prognostic nutritional index in patients with hypopharyngeal squamous cell carcinoma: a retrospective study

Characteristics N (%) PNI P valuea
> 52.0 ≤ 52.0
Age (years)
 ≤ 60 87 46 41  
 > 60 36 13 23 0.090
Sex
 Male 121 (98.4) 59 62  
 Female 2 (1.6) 0 2 0.497
Smoking history
 No 28 (22.8) 13 15  
 Yes 95 (77.2) 46 49 0.853
Alcohol history
 No 41 (33.3) 19 22  
 Yes 82 (66.7) 40 42 0.799
Pharyngolaryngectomy
 Total 51 (41.5) 28 23  
 Partial 72 (58.5) 32 41 0.195
Neck nodal dissection
 Bilateral 42 (34.1) 23 19  
 Unilateral 81 (65.9) 36 45 0.277
Tumor differentiation
 Well/moderate 83 (67.5) 38 45  
 Poor 40 (32.5) 21 19 0.485
Primary tumor site
 Pyriform sinus 108 (87.8) 53 55  
 Posterior wall/postcricoid 15 (12.2) 6 9 0.510
pT classificationb
 T1–T2 87 (70.7) 43 44  
 T3–T4 36 (29.3) 16 20 0.615
pN classificationb
 N0 20 (16.3) 11 9  
 N1–3 103 (83.7) 48 55 0.491
pTNM stagingb
 I–II 18 (14.6) 10 8  
 III–IV 105 (85.4) 49 56 0.486
No. of metastatic LN
 ≤ 3 98 (79.7) 46 52  
 > 3 25 (20.3) 13 12 0.651
LND
 ≤ 0.06 66 (53.7) 31 35  
 > 0.06 57 (46.3) 28 29 0.812
ECS of LN
 Negative 104 (84.6) 50 54  
 Positive 19 (15.4) 9 10 0.955
Surgical margin
 Negative 115 (93.5) 55 60  
 Positive 8 (6.5) 4 4 1.000b
Perineural invasion
 Negative 108 (87.8) 52 56  
 Positive 15 (12.2) 7 8 0.914
Lymphovascular invasion
 Negative 99 (80.5) 46 53  
 Positive 24 (19.5) 13 11 0.498
Adjuvant treatment
 No 8 (6.5) 4 4  
 RT alone 59 (48.0) 30 29  
 CRT 56 (45.5) 29 31 0.796
Disease progression
 Absence 56 (45.5) 38 18  
 Presence 67 (54.5) 21 46 0.000
  1. Italic values indicate significance of p value (p < 0.05)
  2. CRT, combined chemoradiotherapy; ECS, extracapsular spread; LN, lymph node; LND, lymph node density; PNI, prognostic nutritional index; pT classification, pathological tumor classification; pN classification, pathological nodal classification; RT, radiotherapy; TNM, tumor-node-metastasis
  3. aChi-square (χ2) test, P < 0.05
  4. bTumor-node-metastasis staging system proposed by the American Joint Committee on Cancer (7th edition)