Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis

Table 2 Observed and predicted number of R and NR to MTX monotherapy at 6 months using the CCS classifier

Cut off levels were chosen based on the logistic model probabilities of response to MTX of (approximately) > 0.70 for NR and < 0.3 for R. NR and R were defined as described in Additional file 1: Additional Methods