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Table 3 Association between Hippo- and Wnt-related biomarkers and positive/negative outliers (N = 43)

From: Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy

 

PFS (outliers)

Chi-squared test

< 1 quartile

> 3 quartile

p-value

N (%)

N (%)

TAZneg

10 (37.0)

17 (63.0)

0.044

TAZpos

11 (68.8)

5 (31.3)

 

YAPneg

2 (40.0)

3 (60.0)

0.999*

YAPpos

19 (50.0)

19 (50.0)

 

WNTwt

11 (39.3)

17 (60.7)

0.087

WNTmut

10 (66.7)

5 (33.3)

 

Other

14 (40.0)

21 (60.0)

0.021*

TAZpos/WNTmut

7 (87.5)

1 (12.5)

 

Other

12 (41.4)

17 (58.6)

0.159

YAPpos/WNTmut

9 (64.3)

5 (35.7)

 
  1. * Fisher’s exact test
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Journal of Translational Medicine

ISSN: 1479-5876

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