Skip to main content

Advertisement

Table 3 Association between Hippo- and Wnt-related biomarkers and positive/negative outliers (N = 43)

From: Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy

  PFS (outliers) Chi-squared test
< 1 quartile > 3 quartile p-value
N (%) N (%)
TAZneg 10 (37.0) 17 (63.0) 0.044
TAZpos 11 (68.8) 5 (31.3)  
YAPneg 2 (40.0) 3 (60.0) 0.999*
YAPpos 19 (50.0) 19 (50.0)  
WNTwt 11 (39.3) 17 (60.7) 0.087
WNTmut 10 (66.7) 5 (33.3)  
Other 14 (40.0) 21 (60.0) 0.021*
TAZpos/WNTmut 7 (87.5) 1 (12.5)  
Other 12 (41.4) 17 (58.6) 0.159
YAPpos/WNTmut 9 (64.3) 5 (35.7)  
  1. * Fisher’s exact test