Fig. 7From: Enhanced clinical-scale manufacturing of TCR transduced T-cells using closed culture system modulesE6/E7 TCR transduced T-cells secrete large quantities of pro-inflammatory cytokines when co-cultured with cell lines expressing specific target. E6 (a, b) and E7 (c, d) TCR T cells were co-cultured overnight with five target cell lines at a ratio of 1:1. Culture supernatants were analyzed for IFN-γ (top row) and TNF-α (bottom row). Mean and SD of triplicate wells are shown. * Indicates p < 0.05 between selected group versus all negative control groupsBack to article page