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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Enhanced clinical-scale manufacturing of TCR transduced T-cells using closed culture system modules

Fig. 7

E6/E7 TCR transduced T-cells secrete large quantities of pro-inflammatory cytokines when co-cultured with cell lines expressing specific target. E6 (a, b) and E7 (c, d) TCR T cells were co-cultured overnight with five target cell lines at a ratio of 1:1. Culture supernatants were analyzed for IFN-γ (top row) and TNF-α (bottom row). Mean and SD of triplicate wells are shown. * Indicates p < 0.05 between selected group versus all negative control groups

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