Establishment and genomic characterizations of patient-derived esophageal squamous cell carcinoma xenograft models using biopsies for treatment optimization

Table 1 Summary of characteristics of established PDX models for esophageal cancer (all male)

Case no.	Age	Tumor location	Differentiation	Stage	Treatment status
EC1	48	Lower	Poor	IV	Progressive disease
EC2	58	Median	Poor	IV	Before treatment
EC3	41	Lower	Moderate	IV	Before treatment
EC4	58	Lower	Poor	IV	Before treatment
EC5	51	Median	Moderate	IV	Before treatment
EC6	53	Median	Poor	IV	Before treatment
EC7	46	Lower	Moderate	III	Stable disease
EC8	49	Lower	Poor	IV	Before treatment
EC9	57	Median	Moderate	III	Before treatment
EC10	54	Median	Poor	IV	Before treatment
EC11	66	Lower	Poor	IV	Before treatment
EC12	49	Lower	Moderate	IV	Before treatment
EC13	68	Lower	Moderate	IV	Before treatment
EC14	55	Upper	Moderate	IV	Before treatment
EC15	63	NA	Moderate	NA	NA
EC16	62	Median	Poor	NA	NA
EC17	69	Upper	Moderate	IV	Before treatment
EC18	51	Median	Moderate	III	Before treatment
EC19	56	Median	Moderate	IV	Before treatment
EC20	79	Median	Moderate	IV	Before treatment
EC21	66	Lower	Moderate	IV	Stable disease
EC22	53	Lower	Poor	IV	Before treatment
EC23	59	Median	Poor	IV	Before treatment
EC24^a	60	Median	Moderate	IV	Before treatment
EC25^a	68	Lower	Moderate	NA	NA

All cases were of squamous carcinoma with the exception of those noted ^awhich were adenomas
NA non-available

ISSN: 1479-5876