Fig. 1

Classification of γδ T cells towards tumors. Vδ1 γδ T cells and Vδ2 γδ T cells are normal resting γδ T cells before activation or polarization. Following stimulation with different cytokines, resting γδ T cells can polarize into the protumor subgroups: FoxP3+ γδ Treg, γδ T17, or become activated Vδ1 γδ T cells. In addition, resting γδ T cells can also polarize into the antitumor subgroup: γδ Tfh, and γδ T1, or become activated Vδ1 γδ T cells