Table 2 Univariate and multivariate cox regression analyses for recurrence free survival
Risk factors | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | P value | 95% CI | HR | P value | 95% CI | |
MEG3 methylation | 3.624 | 0.040 | 1.060–12.389 | 4.639 | 0.021 | 1.260–17.087 |
IIRC stage (A/B/C/D, E) | 17.901 | < 0.001 | 5.195–61.678 | 7.579 | 0.018 | 1.418–40.511 |
Nodal or distant metastasis (negative, positive) | 12.174 | < 0.001 | 4.725–31.369 | 4.247 | 0.008 | 1.466–12.303 |
Optic nerve invasion (negative, positive) | 13.988 | < 0.001 | 4.072–48.045 | 2.406 | 0.314 | 0.436–13.279 |