Fig. 5From: Hypermethylation of MEG3 promoter correlates with inactivation of MEG3 and poor prognosis in patients with retinoblastomaMEG3 re-expression played an important role in the antitumor effect of 5-Aza-CdR in Weri-Rb1 and Y79 cells. a Si-MEG3 was just offset the MEG3 re-expression effect of 5-Aza-CdR. b Si-MEG3 could block the effect of 5-Aza-CdR on β-catenin expression. c Si-MEG3 could reverse the effect of 5-Aza-CdR on cell proliferation. *P < 0.05Back to article page