Fig. 2From: Hypermethylation of MEG3 promoter correlates with inactivation of MEG3 and poor prognosis in patients with retinoblastomaThe effect of 5-Aza-CdR on MEG3 methylation and MEG3 expression in Weri-Rb1 and Y79 cells. a Hypermethylation of MEG3 promoter was observed in Weri-Rb1 and Y79 cells. 5-Aza-CdR decreased the methylation level of MEG3 promoter. b 5-Aza-CdR down-regulated the expression level of MEG3. *P < 0.05, **P < 0.01Back to article page