From: Comprehensive molecular biomarker identification in breast cancer brain metastases
Case | Copy number state | No. of OMIM genes1 | Important cancer genes | Array nomenclature2 |
---|---|---|---|---|
Jed81_MT | Mosaic-loss | 226 | TP53 | arr[hg19] 17p13.3p11.2(525-20,011,122)x1-2 |
Jed82_MT | Mosaic-loss | 291 | TP53 | arr[hg19] 17p13.3q12(525-32,273,420)x1-2 |
Jed89_MT | Mosaic-loss | 289 | TP53 | arr[hg19] 17p13.3q11.2(525-31,245,235)x1-2 |
Jed82_MT | Loss | 6 | BRCA1 | arr[hg19] 17q21.31(41,251,930-41,829,105)x1 |
Jed81_MT | Gain | 5 | BRCA2 | arr[hg19] 13q13.1q13.2(32,960,791-34,576,864)x3 |
Jed89_MT | Mosaic-loss | 103 | BRCA2 | arr[hg19] 13q11q14.2(19,436,286-47,693,486)x1-2 |
Jed82_MT | Gain | 23 | ERBB2 | arr[hg19] 17q12q21.1(37,063,504-38,179,492)x4 |
Jed81_MT | Mosaic-loss | 435 | IDH1 | arr[hg19] 2q14.3q37.3(123,839,696-242,275,944)x1-2 |
Jed82_MT | Mosaic-loss | 75 | IDH1 | arr[hg19] 2q32.3q35(192,641,695-216,741,600)x1-2 |
Jed89_MT | Gain | 11 | IDH2 | arr[hg19] 15q26.1(90,592,464-91,543,761)x4 |