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Fig. 15 | Journal of Translational Medicine

Fig. 15

From: Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model

Fig. 15

Treatment infliximab or pitrakinra had different effects in NSG mice reconstituted with PBMC from UC patients. mRNA expression levels of TGFß1, HGF, TARC, IFNγ and TNFa as boxplots. Mice were treated as described in Fig. 13. For complete data set see Additional file 1: Tables S4, S5). Lg-delta CT, logarithmic delta cycle threshold. Boxes represent upper and lower quartiles, whiskers represent variability and outliers are plotted as individual points. Unchallenged control (control), challenged control (ethanol + PBS/isotype), challenged and treated (ethanol + infliximab/pitrakinra). For comparison of groups ANOVA followed by TukeyHSD was conducted. Labels given on x- and y-axes on the bottom and the side row apply to all charts

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