Fig. 2

Analysis of CD57+ T-cell levels. a Lower effector memory (TEM) T CD4+ CD157+ cells levels after 48 weeks of suppressive cART in the NRTI-sparing-cART group compared to the NRTI-cART group. Asterisk, p value in bold letters after adjusting for basal CD4, CD8 and nadir CD4 T-cell counts. The subgroup of the NRTI-cART group who switched to a NRTI-sparing-cART regimen for an additional 48 weeks (n = 5, depicted with dotted lines) significantly decreased their TEM CD4+ CD57+ cells to similar levels than the NRTI-sparing-cART group. b Lower total CD8+ CD577+ cells levels in the NRTI-sparing-cART group compared to the NRTI-cART group. Asterisk, p value in bold letters after adjusting for basal CD4, CD8 and nadir CD4 T-cell counts). The subgroup of the NRTI-cART group who switched to a NRTI-sparing-cART regimen for an additional 48 weeks (n = 5, depicted with dotted lines) decreased their memory T CD8+ CD127+ cells to similar levels than the levels NRTI-sparing-cART group; Variables with a p value of < 0.05 were considered statistically significant