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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Increased CD127+ and decreased CD57+ T cell expression levels in HIV-infected patients on NRTI-sparing regimens

Fig. 1

Analysis of CD127+ T-cell levels. a Higher effector memory (TEM) T CD4+ CD127+ cells levels after 48 weeks of suppressive cART in the NRTI-sparing-cART group compared to the NRTI-cART group. Asterisk, p value in bold letters after adjusting for basal CD4, CD8 and nadir CD4 T-cell counts. The subgroup of the NRTI-cART group who switched to a NRTI-sparing-cART regimen for an additional 48 weeks (n = 5, depicted with dotted lines) significantly increased their TEM CD4+ CD127+ cells to similar levels than the NRTI-sparing-cART group. b Higher total CD8+ CD127+ cells levels in the NRTI-sparing-cART group compared to the NRTI-cART group. Asterisk, p value in bold letters after adjusting for basal CD4, CD8 and nadir CD4 T-cell counts. The subgroup of the NRTI-cART group who switched to a NRTI-sparing-cART regimen for an additional 48 weeks (n = 5, depicted with dotted lines) increased their memory T CD8+ CD127+ cells to similar levels than the levels NRTI-sparing-cART group. Variables with a p value of < 0.05 were considered statistically significant

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Journal of Translational Medicine

ISSN: 1479-5876

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