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Table 3 Summary of the transcription factor enrichment analysis results of the four sepsis-associated modules

From: Identification of potential transcriptomic markers in developing pediatric sepsis: a weighted gene co-expression network analysis and a case–control validation study

Modulea

Transcription factor

Official full name

FDR-adjusted P value

Midnight blue

ETS2

ETS proto-oncogene 2, transcription factor

1.64 × 10−2

Brownb

ETS2

ETS proto-oncogene 2, transcription factor

5.85 × 10−8

ELF1

E74 like ETS transcription factor 1

9.52 × 10−6

SPI1

Spi-1 proto-oncogene

4.37 × 10−5

ETV4

ETS variant 4

3.86 × 10−4

RUNX1

Runt related transcription factor 1

1.37 × 10−3

SRF

Serum response factor

1.37 × 10−3

GABPA

GA binding protein transcription factor alpha subunit

2.51 × 10−3

JUN

Jun proto-oncogene, AP-1 transcription factor subunit

3.07 × 10−3

ETV7

ETS variant 7

3.07 × 10−3

IRF family

Interferon regulatory transcription factor family

8.03 × 10−3

SREBF1

Sterol regulatory element binding transcription factor 1

9.52 × 10−3

Tan

IRF1

Interferon regulatory factor 1

4.03 × 10−2

POU5F1

POU class 5 homeobox 1

4.03 × 10−2

POU2F1

POU class 2 homeobox 1

4.03 × 10−2

  1. FDR false discovery rate
  2. aNo significantly enriched transcription factor was identified in module “cyan”
  3. bTranscription factors with FDR-adjusted P value < 0.01 were listed for module “brown” for the sake of brevity