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Table 3 Summary of the transcription factor enrichment analysis results of the four sepsis-associated modules

From: Identification of potential transcriptomic markers in developing pediatric sepsis: a weighted gene co-expression network analysis and a case–control validation study

Modulea Transcription factor Official full name FDR-adjusted P value
Midnight blue ETS2 ETS proto-oncogene 2, transcription factor 1.64 × 10−2
Brownb ETS2 ETS proto-oncogene 2, transcription factor 5.85 × 10−8
ELF1 E74 like ETS transcription factor 1 9.52 × 10−6
SPI1 Spi-1 proto-oncogene 4.37 × 10−5
ETV4 ETS variant 4 3.86 × 10−4
RUNX1 Runt related transcription factor 1 1.37 × 10−3
SRF Serum response factor 1.37 × 10−3
GABPA GA binding protein transcription factor alpha subunit 2.51 × 10−3
JUN Jun proto-oncogene, AP-1 transcription factor subunit 3.07 × 10−3
ETV7 ETS variant 7 3.07 × 10−3
IRF family Interferon regulatory transcription factor family 8.03 × 10−3
SREBF1 Sterol regulatory element binding transcription factor 1 9.52 × 10−3
Tan IRF1 Interferon regulatory factor 1 4.03 × 10−2
POU5F1 POU class 5 homeobox 1 4.03 × 10−2
POU2F1 POU class 2 homeobox 1 4.03 × 10−2
  1. FDR false discovery rate
  2. aNo significantly enriched transcription factor was identified in module “cyan”
  3. bTranscription factors with FDR-adjusted P value < 0.01 were listed for module “brown” for the sake of brevity