Table 1 The tumor growth inhibitions (TGIs) and Ki-67 scores after gimatecan treatment in five xenografts
No. of PDX model | TGIs (%) | Ki-67 (%) | |||
|---|---|---|---|---|---|
Gimatecan | Irinotecan | Control | Gimatecan | Irinotecan | |
1 | 110.1 | 75.4 | –a | –a | –a |
2 | 106.6 | 76.1 | 100 | 60 | 60 |
3 | 84.4 | 24.1 | 70 | 10 | 70 |
4 | 91.7 | 15.1 | 70 | 40 | 60 |
5 | 108.7 | 40.6 | 40 | 10 | 50 |