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Table 2 Genetic profile patients

From: Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease

Gene

SNP

Total

Homozygous: no SNP

Heterozygous, one SNP

Homozygous, two SNPs

IRGM

C

568

430

120

18

ATG16L1

T

559

103

272

184

NOD2

T, C, C

570

428

128

14

rs2066844

T

559

484

71

4

rs2066845

C

567

539

27

1

rs2066847

C

561

513

48

0

XBP1

C, protective

567

510

54

3

LRRK2/MUC19

T

562

532

30

0

CCR6

A

558

135

280

143

IL23R

G, protective

564

524

38

2

STAT3

T

562

218

266

78

NCF4

C

570

282

225

63

  1. Number of patients that could be analysed for each gene, and the distribution of risk alleles in these genes. All numbers are expressed as n