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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Evaluation of the effect of d-amino acid incorporation into amyloid-reactive peptides

Fig. 4

SPECT/CT imaging of radioiodinated aqap5 and AQAp5 in AA and healthy mice. a Radiolabeled aqap5 was observed in the liver (L), spleen (Sp), pancreas (P) and intestine of mice with AA amyloid which persisted for more than 24 h post injection. In contrast, in WT mice, [125I]aqap5 was observed in the hepatic blood pool and kidney (K) at 1 h but was excreted and not visible at 4 h post injection. b [125I]AQAp5 was observed in the liver, spleen, pancreas and intestine of AA mice; whereas, in WT mice free radioiodide liberated during catabolism was observed in the stomach (St) and thyroid (T)

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