Fig. 5
From: Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts
Immunohistological assessment of microvessels and pericytes. a Adjacent immunohistological sections of representative microscopic A-07, D-12, R-18, and U-25 window chamber tumors stained with CD31 to visualize microvessels or αSMA to visualize pericytes. Examples of CD31 positive vessels with or without αSMA staining are highlighted with white or black arrows, respectively. Scale bars, 100 μm. b–d Density of CD31 positive profiles (b), density of αSMA positive profiles (c), and the ratio between αSMA and CD31 positive profiles (d)