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Table 7 Cox analyses of patterns identified using survival tree in the female population, Tehran Lipid and Glucose Study (1999–2014)

From: Application of survival tree analysis for exploration of potential interactions between predictors of incident chronic kidney disease: a 15-year follow-up study

Nodes Number of cases/number of events Pattern description HRs (95% CI) p-value
12 750/43 Age ≤ 45 year, eGFR > 83.5 ml/min/1.73 m2 Reference
4 419/247 Age ≤ 45 year, eGFR ≤ 65 ml/min/1.73 m2 15.18 (10.97–20.99) < 0.001
6 157/41 Age ≤ 29 year, 65 ≤ eGFR ≤ 71 ml/min/1.73 m2 5.07 (3.30–7.77) < 0.001
7 549/220 29 ≤ Age ≤ 45 year, 65 ≤ eGFR ≤ 71 ml/min/1.73 m2 8.78 (6.32–12.15) < 0.001
9 656/166 Age ≤ 45 year, 71 ≤ eGFR ≤ 76 ml/min/1.73 m2 4.93 (3.52–6.90) < 0.001
11 799/124 Age ≤ 45 year, 75 ≤ eGFR ≤ 83.5 ml/min/1.73 m2 2.72 (1.92–3.86) < 0.001
15 152/74 45 ≤ Age < 48 year, eGFR ≤ 69 ml/min/1.73 m2 12.06 (8.28–17.57) < 0.001
16 580/423 Age > 48 year, eGFR ≤ 69 ml/min/1.73 m2 27.25 (19.88–37.34) < 0.001
18 241/97 Age > 45 year, eGFR > 69 ml/min/1.73 m2, SBP ≤ 133 mmHg 8.95 (6.25–12.82) < 0.001
19 140/80 Age > 45 year, eGFR > 69 ml/min/1.73 m2, SBP > 133 mmHg 16.41(11.32–23.80) < 0.001
  1. Column 1 shows the number of terminal nodes of survival tree of Fig. 5 for female population. Column 2 displays the sample size and number of events in each terminal node. Column 3 represents the patterns of each terminal node. Column 4 shows the HR for each node compared to reference node with high survival probability
  2. CI Confidence intervals, HRs Hazard ratio, SBP Systolic blood pressure, eGFR Estimated glomerular filtration rate