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Table 3 Baseline characteristics of the study participants with and without incident CKD, Tehran Lipid and Glucose Study (1999–2014)

From: Application of survival tree analysis for exploration of potential interactions between predictors of incident chronic kidney disease: a 15-year follow-up study

Variables

Men

Women

Non CKD

n = 3002

Incident CKD

n = 793

p-value

Non CKD

n = 2928

Incident CKD

n = 1515

p-value

Age (years)

39.1 (13.3)

50.3 (13.6)

< 0.001

34.2 (10.6)

43.8 (12.4)

< 0.001

Total length of stay in the city (years)

33.1 (12.5)

40.3 (14.1)

< 0.001

28.9 (11.7)

36.5 (13.59)

< 0.001

BMI (kg/m2)

25.7 (4.2)

26.3 (3.9)

< 0.001

26.6 (5.1)

28.1 (4.8)

< 0.001

Waist circumference (cm)

88.5 (11.5)

90.9 (11.1)

< 0.001

84.5 (12.7)

88.9 (12.5)

< 0.001

Wrist circumference (cm)

17.6 (0.9)

17.8 (0.9)

< 0.001

15.7 (1.1)

16.1 (1.1)

< 0.001

Hip circumference (cm)

96.6 (7.3)

97.1 (7.1)

0.086

102.8 (9.5)

104.6 (9.4)

< 0.001

FPG (mmol/l)

4.9 (4.7–5.5)

5.2 (4.8–5.7)

< 0.001

4.8 (4.5–5.2)

4.9 (4.7–5.5)

< 0.001

TG (mmol/l)

1.7(1.1–2.5)

1.8(1.3–2.6)

< 0.001

1.3(0.9–1.9)

1.6 (1.1–2.3)

< 0.001

TC (mmol/l)

5.1 (1.1)

5.3 (1.1)

< 0.001

5.1 (1.1)

5.5 (1.3)

< 0.001

HDL-C (mmol/l)

0.9 (0.2)

0.9 (0.2)

0.48

1.1 (0.3)

1.2 (0.3)

0.210

eGFR (mL/min/1.73 m2)

79.2(10.6)

69.2 (7.4)

< 0.001

77.1 (10.1)

68.8 (7.1)

< 0.001

SBP (mmHg)

117.1 (15.4)

125.2 (19.7)

< 0.001

111.8 (14.9)

120.1 (19.6)

< 0.001

DBP (mmHg)

76.3 (10.3)

80.1(11.6)

< 0.001

74.6 (10.1)

78.2 (10.8)

< 0.001

Heart rate (beats/min)

75.5 (9.8)

74.47 (10.1)

0.015

83.5(11.8)

81.1 (11.4)

< 0.001

Education

 Level 1 (illiterate)

518 (17.3)

221 (27.9)

 

560 (19.1)

455 (30.0)

 

 Level 2 (< 9 years)

1858 (61.9)

370 (46.7)

< 0.001

1884 (64.3)

719 (47.5)

< 0.001

 Level 3 (9–12 years)

528 (17.6)

160 (20.2)

 

361 (12.3)

154 (10.2)

 

 Level 4 (> 12 years)

98 (3.3)

42 (5.3)

 

123 (4.2)

187 (12.3)

 

Marital status

 Single

686 (22.9)

57 (7.2)

 

503 (17.2)

91 (6.0)

 

 Married

2302 (76.7)

725 (91.4)

< 0.001

2325 (79.4)

1273 (84.0)

< 0.001

 Divorced/widowed

14 (0.5)

11 (1.4)

 

100 (3.4)

151 (10.0)

 

FH-CVD in female relatives

200 (6.7)

67 (8.4)

0.080

244 (8.3)

158 (10.4)

0.021

FH-CVD in male relatives

256 (8.5)

54 (6.8)

0.116

213 (7.3)

134 (8.8)

0.064

FHD in first-degree relatives

783 (26.1)

194 (24.5)

0.354

822 (28.1)

456 (30.1)

0.157

PAL

 Inactivea

2009 (71.2)

524 (69.4)

0.331

1908 (70.4)

1017 (70.9)

0.716

Smoking

 Never

1630 (55.1)

437 (56.2)

0.001

2747 (95.1)

1393 (93.6)

 

 Past

378 (12.8)

132 (17.0)

33 (1.1)

24 (1.6)

0.101

 Current

950 (32.1)

208 (26.8)

109 (3.8)

72 (4.8)

 

Use of blood lipid lowering drugs

41 (1.4)

22 (2.8)

0.006

49 (1.7)

65 (4.3)

< 0.001

Use of blood glucose lowering drugs

55 (1.8)

45 (5.7)

< 0.001

54 (1.8)

80 (5.3)

< 0.001

Use of anti hypertensive drugs

59 (2.0)

54 (6.8)

< 0.001

90 (3.1)

132 (8.7)

< 0.001

Use of aspirin

286 (9.5)

108 (13.6)

0.001

172 (5.9)

151 (10.0)

< 0.001

Use of diuretics

12 (0.4)

10 (1.3)

0.004

37 (1.3)

34 (2.2)

0.013

Prevalence CVD

87 (2.9)

53 (6.7)

< 0.001

30 (1.0)

49 (3.2)

< 0.001

  1. Figures are either mean (SD) or N (%) for continuously and categorically distributed variables, respectively
  2. TLGS Tehran Lipid and Glucose Study, BMI body mass index, FPG fasting plasma glucose, TG triglyceride, TC total cholesterol, HDL-C HDL cholesterol, eGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure, FH-CVD family history of premature cardiovascular disease, FHD family history of diabetes mellitus, PAL physical activity level, CVD cardiovascular disease
  3. aDoing exercise or labor less than three times a week or performing activities achieving < 600 metabolic equivalent of task (MET)
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Journal of Translational Medicine

ISSN: 1479-5876

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