Table 6 Distribution of cytokines by autoantibody clusters
From: Cytokine and autoantibody clusters interaction in systemic lupus erythematosus
Cytokine | Neutral (n = 38) | APLA-dominant (n = 13) | dsDNA/ENA-dominant (n = 16) | p-value |
|---|---|---|---|---|
IL-2 | 0 (0) | 2 (15) | 0 (0) | 0.013 |
IL-4 | 2 (5) | 1 (8) | 1 (6) | 0.948 |
IL-5 | 0 (0) | 4 (31) | 2 (12) | 0.003* |
IL-6 | 6 (16) | 5 (38) | 4 (25) | 0.229 |
IL-9 | 1 (3) | 1 (8) | 0 (0) | 0.471 |
IL-10 | 2 (5) | 7 (54) | 5 (31) | 0.0005* |
IL-17A | 6 (16) | 3 (23) | 2 (12) | 0.737 |
TNFα | 2 (5) | 3 (23) | 4 (25) | 0.079 |
G-CSF | 14 (37) | 7 (54) | 10 (62) | 0.186 |
IFNα | 7 (18) | 4 (31) | 6 (37) | 0.299 |
IFNγ | 3 (8) | 1 (8) | 0 (0) | 0.512 |
IL-13 | 0 (0) | 1 (8) | 0 (0) | 0.121 |
IL-1β | 3 (8) | 2 (15) | 1 (6) | 0.652 |
IL-8 | 7 (18) | 4 (31) | 5 (31) | 0.486 |
IL-12/23p40 | 18 (47) | 8 (61) | 9 (56) | 0.632 |