Skip to main content

Table 6 Distribution of cytokines by autoantibody clusters

From: Cytokine and autoantibody clusters interaction in systemic lupus erythematosus

Cytokine Neutral (n = 38) APLA-dominant (n = 13) dsDNA/ENA-dominant (n = 16) p-value
IL-2 0 (0) 2 (15) 0 (0) 0.013
IL-4 2 (5) 1 (8) 1 (6) 0.948
IL-5 0 (0) 4 (31) 2 (12) 0.003*
IL-6 6 (16) 5 (38) 4 (25) 0.229
IL-9 1 (3) 1 (8) 0 (0) 0.471
IL-10 2 (5) 7 (54) 5 (31) 0.0005*
IL-17A 6 (16) 3 (23) 2 (12) 0.737
TNFα 2 (5) 3 (23) 4 (25) 0.079
G-CSF 14 (37) 7 (54) 10 (62) 0.186
IFNα 7 (18) 4 (31) 6 (37) 0.299
IFNγ 3 (8) 1 (8) 0 (0) 0.512
IL-13 0 (0) 1 (8) 0 (0) 0.121
IL-1β 3 (8) 2 (15) 1 (6) 0.652
IL-8 7 (18) 4 (31) 5 (31) 0.486
IL-12/23p40 18 (47) 8 (61) 9 (56) 0.632
  1. Data correspond to number of patients (%)
  2. IL interleukin, G-CSF granulocyte colony-stimulating factor, IFN interferon, TNF tumor necrosis factor
  3. * Statistically significant after Bonferroni correction