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Table 4 Distribution of autoantibodies among autoantibody clusters

From: Cytokine and autoantibody clusters interaction in systemic lupus erythematosus

Autoantibody Neutral (n = 38) APLA-dominant (n = 13) dsDNA/ENA-dominant (n = 16) p-value
ANAs 31 (82) 10 (77) 16 (100) 0.145
RF 12 (32) 5 (38) 7 (44) 0.678
CCP3 1 (3) 0 (0) 0 (0) 0.678
TPOAb 4 (10) 3 (23) 0 (0) 0.129
TgAb 3 (8) 2 (15) 0 (0) 0.289
dsDNA 9 (24) 9 (69) 14 (87) < 0.0001*
ACA-IgM 4 (10) 7 (54) 0 (0) 0.0002*
ACA-IgG 0 (0) 11 (85) 1 (6) < 0.0001*
β2GP1-IgM 2 (5) 4 (31) 1 (6) 0.028
β2GP1-IgG 0 (0) 6 (46) 0 (0) < 0.0001*
RNP 3 (8) 8 (61) 14 (87) < 0.0001*
Ro 13 (34) 5 (38) 8 (50) 0.553
La 1 (3) 0 (0) 4 (25) 0.008
Sm 0 (0) 1 (8) 11 (69) < 0.0001*
  1. Data correspond to number of patients (%)
  2. ANAs antinuclear antibodies, RF rheumatoid factor, CCP3 anti-cyclic citrullinated peptide third-generation, TPOAb anti-thyroperoxidase antibody, TgAb anti-thyroglobulin antibody, dsDNA anti-double stranded DNA antibodies, ACA anticardiolipin antibody, β2GP1 β2 glycoprotein-1
  3. * Statistically significant after Bonferroni correction