|
Composite scorea
|
N
|
CR (%)
|
P
|
P
b
|
OR (95% CI)b
|
|---|
|
0
|
32
|
68.8
| | |
1.00 (reference)
|
|
1
|
77
|
79.2
|
0.246
|
0.270
|
1.767 (0.642–4.865)
|
|
2
|
79
|
94.9
|
0.001
|
0.001
|
8.604 (2.318–31.93)
|
|
3
|
18
|
100
|
0.998
|
0.998
|
–
|
|
1 + 2 + 3
|
174
|
85.4
|
0.005
|
0.008
|
3.624 (1.398–9.395)
|
-
aCombined genotype score model was created by compiling the genotyped data of SNPs rs7278, rs3734703 and rs1042919. Score 1 indicated favorable genotypes (i.e., rs7278 TT/TC genotype, rs3734703 CC/AA genotype, or rs1042919 TT genotype) and a score of 0 indicated unfavorable genotypes (i.e., rs7278 CC genotype, rs734693 CA genotype, or rs1042919 AA/AT genotype). After adding up these scores, four composite score groups were generated: composite score 0, 1, 2 and 3
-
bAdjusted for age, risk stratifications and platelets
