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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Polymorphisms at microRNA binding sites of Ara-C and anthracyclines-metabolic pathway genes are associated with outcome of acute myeloid leukemia patients

Fig. 3

Combined effects of rs10786736, rs3734703 and rs8139 genotypes on survival of AML patients analyzed by the Kaplan–Meier method and log-rank test. A combined genotype score model was created by compiling the genotyped data of SNPs rs10786736, rs3734703 and rs8139. Score 1 indicated favorable genotypes (i.e., rs10786736 CC/CG genotype, rs3734703 CC genotype, or rs8139 TT/CT genotype), and score 0 indicated unfavorable genotypes (i.e., rs10786736 GG genotype, rs3734703 AA/CA genotype, or rs8139 CC genotype). After adding up these scores, four composite score groups were generated: composite score 0, 1, 2 and 3

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