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Table 3 Bias, precision and accuracy of each model in the external validation data set

From: Improving precision of glomerular filtration rate estimating model by ensemble learning

Variable

Measured GFR (ml/min/1.73 m2)

Overall

< 30

≥ 30 and < 60

≥ 60

Bias = median difference (95% CI)

 Regression model

2.3 (1.0–3.4)

4.4 (2.9–5.9)

3.1 (1.5–6.5)

−1.9 (−4.5 to 0.9)

 ANN model

3.2 (2.2–5.4)

5.4 (3.1–7.4)

5.4 (2.4–7.6)

0.8 (−3.9 to 2.7)

 SVM model

3.6 (2.6–4.9)

6.8 (4.9–9.0)

4.0 (2.2–6.4)

−0.2 (−2.3 to 2.6)

 Ensemble model

3.4 (2.3–4.4)

5.6 (3.7–8.2)

4.0 (2.1–6.7)

−0.5 (−3.9 to 2.3)

Precision = IQR of the difference (95% CI)

 Regression model

14.0 (12.4–15.9)

9.2 (7.3–11.8)

13.5 (11.2–18.0)

19.6 (16.8 to 23.5)

 ANN model

15.1 (13.6–17.0)

11.1 (9.1–14.8)

14.9 (13.1–17.7)

20.5 (17.9 to 25.1)

 SVM model

14.2 (12.4–16.0)

9.5 (7.5–12.1)

12.9 (10.3–16.2)

18.5 (14.9 to 21.5)

 Ensemble model

13.5 (11.8–14.9)

8.9 (7.0–11.0)

12.7 (10.4–16.0)

17.9 (15.44 to 21.9)

Accuracy = 30% accuracy (95% CI)

 Regression model

75.1 (70.7–79.4)

52.4 (42.7–61.2)

75.2 (67.8–81.9)

89.1 (83.6 to 93.3)

 ANN model

73.4 (69.0–77.2)

54.4 (44.7–64.1)

70.5 (63.11–77.2)

87.9 (82.4 to 92.1)

 SVM model

73.1 (68.8–77.2)

47.6 (37.9–57.3)

71.1 (63.11–77.9)

90.9 (86.1 to 94.5)

 Ensemble model

75.5 (71.5–79.6)

52.4 (42.7–62.1)

73.8 (65.11–79.9)

91.5 (86.7 to 95.2)

  1. GFR glomerular filtration rate, ANN artificial neural network, SVM support vector machine, IQR interquartile range, CI confidence interval
  2. P < 0.05 compared with regression model-GFR