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Table 2 Patient characteristics in the development and validation datasets

From: Improving precision of glomerular filtration rate estimating model by ensemble learning

Characteristic

Development (N = 1002)

External validation (N = 417)

P value#

Age (years)

55.7 ± 15.0

51.3 ± 16.0

< 0.001

Male proportion

570 (56.9)

262 (62.8)

0.044

Diabetes

500 (49.9)

97 (23.2)

< 0.001

Body mass index (kg/m2)

24.0 ± 3.7

22.9 ± 3.6

< 0.001

Weight (kg)

63.7 ± 12.3

61.5 ± 11.8

0.002

Height (cm)

162.5 ± 8.3

163.6 ± 7.6

0.020

Body-surface area (m2)

1.7 ± 0.2

1.7 ± 0.2

0.107

Serum creatinine (mg/dl)

1.7 ± 1.8

2.7 ± 2.5

< 0.001

Measured GFR

 Mean (ml/min/1.73 m2)

70.0 ± 29.6

53.4 ± 26.5

< 0.001

 < 15 (ml/min/1.73 m2)

10 (1.0)

9 (2.2)

< 0.001

 ≥ 15 and < 30 (ml/min/1.73 m2)

99 (9.9)

94 (22.5)

 

 ≥ 30 and < 60 (ml/min/1.73 m2)

275 (27.4)

149 (35.7)

 

 ≥ 60 and < 90 (ml/min/1.73 m2)

345 (34.4)

123 (29.5)

 

 ≥ 90 (ml/min/1.73 m2)

273 (27.2)

42 (10.1)

 
  1. Unless otherwise noted, data are reported as N (percentage); continuous variables are mean ± standard deviation
  2. GFR glomerular filtration rate
  3. #P values were derived from paired-sample t test