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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: The macrophage C-type lectin receptor CLEC5A (MDL-1) expression is associated with early plaque progression and promotes macrophage survival

Fig. 6

MDL-1 overexpression reduces apoptosis-associated molecule expression in macrophages under ox-LDL stimulation. a Representative Western blot analyses of cleaved caspase-3 and caspase-3 expression in cell lysates from peritoneal macrophages treated with 50 μg/mL ox-LDL with or without pretreatment of adenovirus overexpressing MDL-1 (Ad-MDL-1) or control virus (Ad-null) in RPMI 1640 media. Images are representative of three independent experiments. Quantification of band densitometry is shown in b. Values are expressed as mean ± SEM. *p < 0.05 compared with Ad-null or ox-LDL with Ad-null treatment group

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