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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: The macrophage C-type lectin receptor CLEC5A (MDL-1) expression is associated with early plaque progression and promotes macrophage survival

Fig. 5

MDL-1 overexpression promotes macrophage survival under ox-LDL stimulation. a Western-blot analysis of MDL-1 expression in peritoneal macrophages after infected with adenovirus overexpressing MDL-1 (Ad-MDL-1) or control virus (Ad-null). b Macrophage apoptosis (green) measured by TUNEL assay of peritoneal macrophages stimulated with 50 μg/mL ox-LDL with or without pretreatment with Ad-MDL-1 or Ad-null in RPMI 1640 media. Nuclei were costained with DAPI (blue). Quantification of tunel assay from each group (n ≥ 3/group) was performed in (c). Values are expressed as mean ± SEM. *p < 0.05 compared with ox-LDL with Ad-null treatment group; # p < 0.01 compared with PBS or Ad-null group

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