From: Management and potentialities of primary cancer cultures in preclinical and translational studies
Tumor origin | Origin of species | Sample | Zebrafish line | No. of cells | Stage | Site of injection | References |
---|---|---|---|---|---|---|---|
Abdominal liposarcoma | Human | SR | Tg(Kdrl:mCherry) | 50–400 | Embryo (2 dpf) | Heart cavity | [105] |
Acinar cell carcinomas | Zebrafish | SR | tg(CB1) | 2/3 × 105 and fragments | Larvae (7–14 dpf)/adult | Intraperitoneal/abdomen and dorsal muscles | [159] |
Acute lymphoblastic leukemia | Zebrafish | SR | AB and EK | 5 × 105 | Adult | Intraperitoneum | [160] |
Acute myeloid leukemia | Human | BM | AB | 100–200 | Blastula (3 hpf) | Yolk sac | [161] |
Ampulla of Vater adenocarcinoma | Human | SR | Tg(fli1:eGFP)/alb(albinos) | Â | Embryo (2Â dpf) | Yolk sac | [162] |
Ampulla of Vater adenocarcinoma | Human | SR | Tg(fli1:eGFP) | Fragments | Embryo (2Â dpf) | Yolk sac | [163] |
Bone metastasis | Human | SR | Tg(fli1:eGFP) | 50–400 | Embryo (2 dpf) | Duct of Cuvier | [72] |
Colon adenocarcinoma | Human | SR | Tg(fli1:eGFP)/alb(albinos) | Â | Embryo (2Â dpf) | Yolk sac | [162] |
Ependymoma | Mouse | SR | Tg(fli1:eGFP) | 2 × 105 | Juvenile (30 dpf) | Cerebral hemisphere | [164] |
Glioblastoma | Human | SR | AB | Â | Embryo (2Â dpf)/adult | Brain ventricle | [165] |
Glioblastoma | Mouse | SR | Tg(fli1:eGFP) | 2 × 105 | Juvenile (30 dpf) | Cerebral hemisphere | [164] |
Liver metastasis from NET | Human | SR | Tg(fli1:eGFP) | 100 | Embryo (2Â dpf) | Perivitelline space | [166] |
Melanoma | Zebrafish | SR | Casper | 2 × 105 | Adult | Peritoneal cavity/intracardiac cavity | [167] |
Multiple myeloma | Human | Pl | Casper | 100 | Embryo (2Â dpf) | Perivitelline space | [168] |
Myeloid leukemia | Human | PB | AB | 50–200 | Embryo (2 dpf) | Posterior cardinal vein | [169] |
Pancreatic cancer | Human | SR | Tg(fli1:eGFP)/alb(albinos) | Â | Embryo (2Â dpf) | Yolk sac | [162] |
Pancreatic cancer | Human | SR | Tg(fli1:eGFP) | Fragments | Embryo (2Â dpf) | Yolk sac | [163] |
Papillary thyroid cancer | Human | SR | Tg(fli1a:EGFP)y1 | 100 | Embryo (2Â dpf) | Perivitelline space | [170] |
Pituitary adenoma | Human | SR | Tg(fli1:eGFP) | 100 | Embryo (2Â dpf) | Perivitelline space | |
Prostate cancer | Human | SR | Casper | Â | Embryo (2Â dpf)/juvenile | Sinus venous/subcutaneous injection | [173] |
Rhabdomyosarcoma | Zebrafish | SR | AB | 10–2 × 104 | Adult | Intraperitoneal cavity | [174] |
Stomach adenocarcinoma | Human | SR | Tg(fli1:eGFP)/alb(albinos) | Â | Embryo (2Â dpf) | Yolk sac | [162] |
Testicular germ cell tumor | Zebrafish | SR | AB/TU | 5 × 103 | Adult | Intraperitoneal cavity | [175] |